I have a Simian crease on both hands. Can anyone tell me its significance? Both its pros and cons. - Quora
![Single Transverse Palmar crease in 5% of intants inherited familialy and in Down's Syndrome. | Neonatal nurse, Pediatric care, School of medicine Single Transverse Palmar crease in 5% of intants inherited familialy and in Down's Syndrome. | Neonatal nurse, Pediatric care, School of medicine](https://i.pinimg.com/originals/4f/e5/7f/4fe57f9fae42a04eafc797bca2bf81a4.jpg)
Single Transverse Palmar crease in 5% of intants inherited familialy and in Down's Syndrome. | Neonatal nurse, Pediatric care, School of medicine
![The simian crease: Relationship to various genetic disorders - Wahl - 2019 - Clinical Anatomy - Wiley Online Library The simian crease: Relationship to various genetic disorders - Wahl - 2019 - Clinical Anatomy - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/01262c41-b467-4572-98c2-cfb8162a5a0d/ca23432-fig-0003-m.jpg)
The simian crease: Relationship to various genetic disorders - Wahl - 2019 - Clinical Anatomy - Wiley Online Library
![Assessment of the Newborn: Physical Anomalies and Neurologic Issues, Palmar crease, Simian crease, and Pilonidal sinus | Alexander Street, part of Clarivate Assessment of the Newborn: Physical Anomalies and Neurologic Issues, Palmar crease, Simian crease, and Pilonidal sinus | Alexander Street, part of Clarivate](https://d3crmev290s45i.cloudfront.net/frames/1008357xxx/1008357363/1008357363-disc001-file001-frame00010-size-original.jpg)
Assessment of the Newborn: Physical Anomalies and Neurologic Issues, Palmar crease, Simian crease, and Pilonidal sinus | Alexander Street, part of Clarivate
![The simian crease: Relationship to various genetic disorders - Wahl - 2019 - Clinical Anatomy - Wiley Online Library The simian crease: Relationship to various genetic disorders - Wahl - 2019 - Clinical Anatomy - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/5fa88f82-c9f7-49b2-937b-3624ccd35b4e/ca23432-fig-0002-m.jpg)